The Faculty of Science was founded in 1937 as one of the Higher Schools of Gordon Memorial College. In 1945 these schools came under a single independent administration. In 1947 the School of Science became the Faculty of Science and continued to maintain this name until the University College of Khartoum became the University of Khartoum in 1956.

* The Faculty is located within the central campus.

The Faculty has (54) members in its teaching staff:-
(1) Emeritus Professor (Prof. Mustafa Hassan)
(7) Professors
(23) Associate Professors
(14) Assistant Professors
(9) Lecturers

The Faculty has (24) teaching assistants and (16) technicians.

The total enrollment of the students in the Faculty is (1744) students in all specializations. For the year 1997-1998, (224) students graduated with B.Sc. General and Honours degree. Since the commencement of the postgraduate studies in the Faculty, (505) students were awarded M.Sc. and (105) students were awarded Ph.D. degrees.

There are teaching laboratories in the faculty at all levels: for Physics, Chemistry, Geology, Botany and Zoology. Each laboratory accommodates between (60-160) students, in addition to a number of reseach laboratories for research by members of the academic staff and post graduate students.

Each of the five departments has its own specialized library that accommodates between  (40-120) students. They serve graduate and post graduate students as well as  members of the academic staff, as well as research students and teaching staff from other universities.

Members of the academic staff and post graduate students of the Faculty conduct a wide range of researches and studies, particularly in the fields of Bilharzia, Wild Animals, Marine Sciences, Hydrology, Petroleum, Geological Engineering, Theoretical Physics, Nuclear Physics, Solid State Physics, Materials Science. Analysis of Materials.

The Faculty sustains relations with various universities and academic centers in foreign countries,  including in The Netherlands, Germany, France and Sweden. The Faculty undertakes jointly approved academic programmes or common research projects with these universities and academic centers. An active cooperation relation is maintained with  the University of Leiden, The Netherlands The Faculty also maintains relations with the International Centre for Theoretical Physics (ICTP) in Italy and the International Atomic Energy Agency (Vienna Considerable benefits have been derived from these relations illustrated in the acquisition  of advanced scientific equipment and materials, and the exchange of visits by experts and scholars from both sides.